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Record #50215

Polymerase θ inhibition activates the cGAS-STING pathway and cooperates with immune checkpoint blockade in models of BRCA-deficient cancer

Original paper date
Mar 13, 2023
Institution
Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA · Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA 02115, USA · Department of Radiation Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02215, USA · Department of Surgical Oncology and Harvard Medical School, Brigham and Women’s Hospital, Boston, MA 02115, USA · Department of Medicine, Division of Hematology-Oncology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA · Hale Family Center for Pancreatic Cancer Research, Dana-Farber Cancer Institute, Boston, MA 02215, USA · Department of Medicine, Division of Gastroenterology, Abramson Family Cancer Research Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA · Center for DNA Damage and Repair, Dana-Farber Cancer Institute, Boston, MA 02215, USA
Open access
No
Article type
Research Article
Broad categories
(BLS) Biochemistry(BLS) Biology - Cancer(BLS) Biology - Cellular(BLS) Genetics
Notes from Retraction Watch

see also: https://pubpeer.com/publications/EB04F1E734D3E88825F3B712FA4F89

Citation lifecycle

How this paper is being cited

Pre-retraction
5
Same day
0
Post-retraction
11
% post-retraction
68.8%
~6.7 citations/yr before retraction · ~4.0 citations/yr after
— citing papers

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